Fewer men than women develop allergic asthma after puberty because of the protection they receive from testosterone, the team said.
What is allergic asthma?
Allergic asthma is an inflammatory condition that causes the airways to swell, making it difficult to breathe.
According to an international team of researchers, testosterone stimulates the development of male sexual characteristics and suppresses the production of the immune cell type, which causes allergic asthma.
The researchers found that higher testosterone levels in mice helped stop the production of immune cells called congenital lymphoid cells.
- ILC2 is found in the lungs, skin and other organs more you can check here.
These cells produce inflammatory proteins that can cause inflammation of the lungs and be damaged when exposed to common causes of allergic asthma such as pollen, dust mites, cigarette smoke and pet hair.
The results of the study are based on experiments performed on mice.
- “There is a very interesting clinical observation that women are more susceptible to the disease and develop more severe bronchial asthma than men, so we tried to understand why this happens,” said study leader Cyril Silet of the Walter and Eliza Hall Institute in Melbourne Australia.
- The full report you can check here.
- “Our research shows that high testosterone levels in men prevent them from developing allergic asthma,” Seylett says..